We have implemented commercial scale manufacturing of second-generation biomass-derived chemicals, with novel technologies in bio-solvents by converting biomass to derivatives of levulinic acid, originally developed by GFBiochemicals. Products that are now commercially available include ethyl levulinate, butyl levulinate, levulinate propanediol ketal and levulinate glycerol ketal. Levulinic acid derivatives are considered key technologies for moving towards petrochemical-free chemistry, but commercial-scale production has long been hampered by the struggle between capital investment and market demand. Produced from agricultural waste, derivatives of levulinic acid such as butyl levulinate and ethyl levulinate propanediol ketal can be used as ...